Which President was assassinated during his term in office?

The correct answer encompasses all three Presidents: James A. Garfield, William McKinley, and John F. Kennedy, each of whom was assassinated while in office.

James A. Garfield was shot in July 1881 and succumbed to his wounds later that fall. He is often remembered for the challenges he faced during a short presidency and the circumstances surrounding his assassination, which drew attention to issues of political corruption and the need for reform.

William McKinley was assassinated in September 1901, when he was shot by an anarchist during a public event. He died a week later due to complications from his injuries. His assassination highlighted the era's political tensions and had significant implications for the nation's policy direction, particularly under his successor, Theodore Roosevelt.

John F. Kennedy was assassinated in November 1963 during a motorcade in Dallas, Texas. His death shocked the nation and had a profound impact on American politics, culture, and society. The circumstances surrounding his assassination continue to influence conspiracy theories and public discourse.

Thus, all three Presidents listed were assassinated during their terms, making the option that includes all of them the correct choice.